10-KPeriod: FY2023

AbbVie Inc. Annual Report, Year Ended Dec 31, 2023

Filed February 20, 2024For Securities:ABBV

Summary

AbbVie Inc. reported total net revenues of $54.3 billion for the fiscal year ended December 31, 2023, a decrease of 6.4% on a reported basis compared to the prior year. This decline was primarily driven by the impact of biosimilar competition for Humira, which accounted for approximately 27% of AbbVie's total net revenues in 2023 and faced significant erosion in the US market following the loss of exclusivity in January 2023. Despite the Humira headwinds, AbbVie demonstrated strong performance in its growth products, particularly Skyrizi and Rinvoq, which saw substantial revenue increases of 50.3% and 57.4%, respectively. The company's oncology, aesthetics, and neuroscience portfolios also showed positive growth. AbbVie is strategically investing in its pipeline, evidenced by its approximately 90 compounds in development, and has recently completed the acquisition of ImmunoGen and announced plans to acquire Cerevel Therapeutics, signaling a continued focus on diversification and expansion into new therapeutic areas. The company also continues to return value to shareholders through dividends and share repurchases, with a quarterly dividend increase announced in October 2023.

Financial Statements
Beta
Revenue$54.32B
Cost of Revenue$20.41B
Gross Profit$33.90B
SG&A Expenses$12.87B
Operating Expenses$41.56B
Operating Income$12.76B
Interest Expense$2.22B
Net Income$4.86B
EPS (Basic)$2.73
EPS (Diluted)$2.72
Shares Outstanding (Basic)1.77B
Shares Outstanding (Diluted)1.77B

Key Highlights

  • 1AbbVie's total net revenues decreased by 6.4% to $54.3 billion in 2023, primarily due to the loss of Humira exclusivity and subsequent biosimilar competition, which impacted US sales significantly.
  • 2Skyrizi and Rinvoq, key growth drivers for AbbVie, experienced robust revenue increases of 50.3% and 57.4% respectively, demonstrating strong market uptake and indication expansion.
  • 3The oncology portfolio, including Imbruvica and Venclexta, saw a revenue decline of 21.3% and a growth of 13.9%, respectively, with Imbruvica facing demand and market share challenges.
  • 4Aesthetics and Neuroscience segments showed positive growth, with Botox Cosmetic up 2.6% and Vraylar revenue increasing by 35.4%, driven by market growth and new indications.
  • 5The company is actively expanding its pipeline and business through strategic acquisitions, notably the completion of the ImmunoGen acquisition and the proposed acquisition of Cerevel Therapeutics.
  • 6AbbVie's research and development expenses increased by 18% to $7.7 billion, reflecting continued investment in its pipeline of approximately 90 compounds in development.
  • 7The company returned significant capital to shareholders through dividends ($10.5 billion) and share repurchases ($1.6 billion) in 2023, while also managing its debt profile.

Frequently Asked Questions

AbbVie reported total net revenues of $54.3 billion for 2023, a decrease of 6.4% compared to 2022, primarily due to the impact of Humira biosimilar competition. Diluted earnings per share were $2.72.

Humira sales decreased by 32.2% globally in 2023, with a 34.7% decrease in the United States following the loss of exclusivity in January 2023. AbbVie anticipates continued revenue decline for Humira due to biosimilar competition.

AbbVie's key growth drivers are Skyrizi and Rinvoq, which showed strong revenue growth in 2023. Strategic priorities include maximizing diversified revenue, driving growth through new product launches and indication expansions, investing in its pipeline across immunology, oncology, aesthetics, and neuroscience, and returning cash to shareholders.

AbbVie completed the acquisition of ImmunoGen for approximately $10.1 billion in February 2024 and announced its definitive agreement to acquire Cerevel Therapeutics for approximately $8.7 billion in December 2023, signaling continued investment in oncology and neuroscience.