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10-KPeriod: FY2005

AMGEN INC Annual Report, Year Ended Dec 31, 2005

Filed March 10, 2006For Securities:AMGN

Summary

Amgen Inc. reported strong financial performance for the fiscal year ending December 31, 2005, with total revenues reaching $12.43 billion and net income of $3.67 billion. The company's growth was primarily driven by its key products: Aranesp®, Enbrel®, and Neulasta®. Amgen continues to invest heavily in research and development, with plans for a significant increase in R&D expenses in 2006 to support its expanding pipeline, particularly for the osteoporosis drug denosumab. The company also announced its intent to acquire Abgenix, Inc. for approximately $2.2 billion, which would further bolster its pipeline with the co-developed drug panitumumab. While the company experienced robust sales growth, it also faces increasing competition, particularly from biosimilar products in Europe, and potential impacts from changes in reimbursement policies, notably the Medicare Modernization Act. Amgen is actively managing its manufacturing capacity and supply chain to meet demand and mitigate risks. The company also continued its share repurchase program, returning significant capital to shareholders.

Key Highlights

  • 1Total revenues grew 20% to $12.43 billion in 2005, with net income at $3.67 billion.
  • 2Key products Aranesp®, Enbrel®, and Neulasta® were major drivers of sales growth.
  • 3Amgen plans a 30-40% increase in R&D expenses for 2006, reflecting significant investment in its pipeline.
  • 4The company announced its intention to acquire Abgenix, Inc. for approximately $2.2 billion to gain full ownership of panitumumab and denosumab.
  • 5Amgen is facing increased competition from biosimilars in Europe, with potential introductions in late 2006/2007.
  • 6The company returned $4.43 billion to shareholders through its stock repurchase program in 2005.
  • 7The company is expanding its manufacturing capacity, including a new facility planned in Ireland.

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