Early Access

10-KPeriod: FY2012

AMGEN INC Annual Report, Year Ended Dec 31, 2012

Filed February 27, 2013For Securities:AMGN

Summary

Amgen Inc. reported robust revenue growth of 11% for the fiscal year 2012, reaching $17.265 billion. This growth was primarily driven by strong performance across its key products, including Neulasta®, Enbrel®, XGEVA®, and Prolia®, which saw significant increases in sales. The company also continued its commitment to returning capital to shareholders through a substantial stock repurchase program and an increased quarterly dividend. Amgen made significant progress in its R&D pipeline, advancing several promising candidates, such as AMG 145, brodalumab, romosozumab, and rilotumumab, into Phase 3 clinical trials. However, the company faces challenges including upcoming patent expirations for key products like NEUPOGEN® and Aranesp®, which are expected to increase competition from biosimilars. Additionally, evolving reimbursement landscapes and ongoing regulatory scrutiny, particularly concerning Enbrel® and its erythropoiesis-stimulating agents (ESAs), present potential headwinds.

Financial Statements
Beta
Revenue$17.27B
Cost of Revenue$3.20B
Gross Profit$14.07B
SG&A Expenses$4.81B
Operating Expenses$11.69B
Operating Income$5.58B
Interest Expense$1.05B
Net Income$4.34B
EPS (Basic)$5.61
EPS (Diluted)$5.52
Shares Outstanding (Basic)775.00M
Shares Outstanding (Diluted)787.00M

Key Highlights

  • 1Total revenues increased by 11% to $17.265 billion in 2012, driven by strong product sales.
  • 2Key products like Neulasta® (up 4%), Enbrel® (up 14%), XGEVA® (up over 100%), and Prolia® (up over 100%) showed significant sales growth.
  • 3Amgen advanced several product candidates (AMG 145, brodalumab, romosozumab, rilotumumab) into Phase 3 clinical trials, bolstering its future pipeline.
  • 4The company returned significant capital to shareholders, repurchasing $4.7 billion in stock and increasing its quarterly dividend by 31%.
  • 5Patent expirations for NEUPOGEN® (December 2013) and Aranesp® are anticipated, leading to increased competition from biosimilars, particularly in the US.
  • 6Sales of ESAs (Aranesp® and EPOGEN®) continued to decline due to regulatory label changes and reimbursement pressures.
  • 7Amgen acquired Mustafa Nevzat Pharmaceuticals and Micromet Inc. in 2012, expanding its reach and capabilities.

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