10-KPeriod: FY2024

AMGEN INC Annual Report, Year Ended Dec 31, 2024

Filed February 14, 2025For Securities:AMGN

Summary

Amgen Inc. reported robust total revenue growth of 19% for the fiscal year 2024, reaching $33.42 billion. This growth was primarily driven by a 23% increase in product sales volume, boosted significantly by the acquisition of Horizon Therapeutics, which contributed $4.2 billion to sales. Key products like Repatha and TEZSPIRE showed strong performance, with sales increasing by 36% and 71% respectively. However, established products like ENBREL experienced a 10% decline in sales, reflecting ongoing competitive pressures and net selling price decreases. Amgen continued its strategic investment in R&D, with expenses increasing by 25% to $5.96 billion, indicating a strong commitment to pipeline development. The company also focused on debt reduction and returning capital to shareholders, with a 6% increase in its quarterly dividend.

Financial Statements
Beta
Revenue$33.42B
Cost of Revenue$12.86B
Gross Profit$20.57B
SG&A Expenses$7.10B
Operating Expenses$26.17B
Operating Income$7.26B
Interest Expense$3.15B
Net Income$4.09B
EPS (Basic)$7.62
EPS (Diluted)$7.56
Shares Outstanding (Basic)537.00M
Shares Outstanding (Diluted)541.00M

Key Highlights

  • 1Amgen reported a 19% increase in total revenues to $33.42 billion for FY2024, driven by a 23% rise in product sales volume.
  • 2The acquisition of Horizon Therapeutics contributed $4.2 billion to sales in 2024.
  • 3Strong sales growth was observed in Repatha (36% increase) and TEZSPIRE (71% increase).
  • 4ENBREL sales declined by 10% due to lower net selling prices.
  • 5R&D expenses increased by 25% to $5.96 billion, signaling continued investment in pipeline development.
  • 6Amgen increased its quarterly dividend by 6% and continues to focus on debt reduction and capital allocation.
  • 7The company is facing patent expirations for Prolia and XGEVA in early 2025, anticipating biosimilar competition and sales erosion.

Frequently Asked Questions

Amgen's revenue growth in 2024 was primarily driven by a significant increase in product sales volume (23%), largely propelled by the acquisition of Horizon Therapeutics, which added $4.2 billion in sales. Additionally, strong performance from key products like Repatha and TEZSPIRE contributed to the overall revenue increase.

Amgen anticipates sales erosion for Prolia and XGEVA starting in early 2025 due to biosimilar competition, as their patents for RANKL antibodies expire in the U.S. in February 2025 and in select European countries in November 2025.

Amgen increased its R&D expenses by 25% to $5.96 billion in 2024, demonstrating a continued strong commitment to its pipeline. The company is advancing several promising product candidates, including notable progress in Phase 2 and Phase 3 trials for treatments in areas like obesity, autoimmune diseases, and oncology.

Amgen highlighted several key risks, including increasing competition from biosimilars and generics, pricing and reimbursement pressures from third-party payers, potential tax liabilities related to an ongoing IRS dispute, and risks associated with its global operations, supply chain, and cybersecurity. The company also noted the impact of the Inflation Reduction Act (IRA) on future drug pricing.