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Moderna, Inc. Quarterly Report for Q2 Ended Jun 30, 2025

Filing Date
Filed August 1, 2025
Period End
June 30, 2025
Security
MRNA
In the record · 2018–202610-K910-Q238-K117

MRNA filed 9 annual reports (10-K), 23 quarterly reports (10-Q) and 117 current reports (8-K) between 2018 and 2026.

  1. Material agreement8-K · Aug ’20Aug ’20
  2. Leadership change8-K · Sep ’22Sep ’22
  3. Leadership change8-K · Sep ’26Sep ’26

Summary

Summary of the 10-Q filed August 1, 2025. Cited figures are marked; the original filing is the authoritative source.

Moderna, Inc. reported a net loss of $825 milliona ($2.13 per share) for the second quarter of 2025, a significant improvement from the $1.279 billion ($3.33 per share) net loss in the same period last year.

Total revenue for the quarter was $142 millionb, down 41% year-over-year, primarily driven by a 38% decrease in net product sales to $114 million. This decline in product sales is attributed to lower COVID-19 vaccination rates and reduced average selling prices, particularly in the U.S. market. Despite the revenue challenges, the company continues to invest heavily in its R&D pipeline, with expenses decreasing by 43% year-over-year to $700 million, reflecting strategic prioritization and operational efficiencies.

The company's balance sheet remains robust, with $1.279 billionc in cash and cash equivalents and substantial investments totaling $6.2 billion. Moderna has also seen progress with new product approvals, including its next-generation COVID vaccine, mNEXSPIKE, and expanded indications for its RSV vaccine, mRESVIA, positioning it for potential future growth as the COVID-19 market transitions to a seasonal offering.

Key Highlights

  1. Net loss for Q2 2025 improved to $825 million from $1.279 billion in Q2 2024.
  2. Total revenue decreased by 41% to $142 million in Q2 2025, driven by a 38% drop in net product sales to $114 million.
  3. Research and development expenses were reduced by 43% to $700 million in Q2 2025, reflecting pipeline prioritization and cost management.
  4. The company received FDA approval for its next-generation COVID vaccine, mNEXSPIKE (mRNA-1283), in May 2025.
  5. FDA expanded the indication for the RSV vaccine, mRESVIA, in June 2025 to include younger adults with increased risk.
  6. Cash and cash equivalents stood at $1.279 billion as of June 30, 2025, with total investments of $6.2 billion.
  7. The company continues to manage its pipeline, with programs in respiratory viruses, latent/other viruses, oncology, and rare diseases, including positive Phase 3 results for a seasonal flu vaccine candidate (mRNA-1010).

Financial Statements

Q2 FY2025 against Q2 FY2024

Line itemQ2 FY2025Q2 FY2024Change
Revenue$142.00M$241.00M−41.1%
Cost of Revenue$119.00M$115.00M+3.5%
Gross Profit$23.00M$126.00M−81.7%
R&D Expenses$700.00M$1.22B−42.7%
Operating Expenses$1.05B$1.60B−34.6%
Operating Income-$907.00M-$1.36B+33.5%
Net Income-$825.00M-$1.28B+35.5%
EPS (Basic)$-2.13$-3.33+36.0%
EPS (Diluted)$-2.13$-3.33+36.0%
Shares Outstanding (Basic)388.00M384.00M+1.0%
Shares Outstanding (Diluted)388.00M384.00M+1.0%

Frequently Asked Questions

  1. What is the primary driver behind the decline in Moderna's revenue?

    Moderna's revenue decline, particularly in net product sales, is primarily driven by lower COVID-19 vaccination rates and a decrease in the average selling price for its COVID vaccines. The market is transitioning to a seasonal commercial pattern, leading to reduced demand compared to previous periods.

  2. How is Moderna managing its significant research and development (R&D) expenses?

    Moderna is actively managing its R&D expenses through disciplined cost management, portfolio prioritization, and a focused approach to pipeline execution. This includes operational efficiencies, resourcing adjustments, and a strategic focus on advancing key late-stage programs while streamlining other areas.

  3. What are the key product developments mentioned in this report?

    Key product developments include the FDA approval of mNEXSPIKE (mRNA-1283), Moderna's next-generation COVID vaccine, in May 2025, and the expanded indication for mRESVIA, its RSV vaccine, in June 2025. The company also announced positive Phase 3 efficacy results for its seasonal influenza vaccine candidate (mRNA-1010) and is advancing its oncology and rare disease pipelines.

  4. What is Moderna's current liquidity position?

    As of June 30, 2025, Moderna reported $1.279 billion in cash and cash equivalents. The company also holds substantial investments totaling $6.2 billion (including current and non-current marketable securities). Moderna believes these resources, along with anticipated cash from product sales, will be sufficient to fund its operations for at least the next 12 months.