10-QPeriod: Q1 FY2020

BeOne Medicines Ltd. Quarterly Report for Q1 Ended Mar 31, 2020

Filed May 11, 2020For Securities:ONCBEIGF

Summary

BeOne Medicines Ltd. reported a significant increase in cash and cash equivalents to $1.96 billion as of March 31, 2020, driven by substantial financing activities, including a major collaboration with Amgen that provided $2.78 billion in proceeds. Despite this strong liquidity, the company incurred a net loss of $364.9 million for the first quarter of 2020, a notable increase from the prior year's loss of $168.1 million. This widened loss is primarily attributed to a substantial rise in research and development (R&D) expenses, which increased by 70.6% to $304.3 million, and a significant increase in selling, general, and administrative (SG&A) expenses, up 85.8% to $107.1 million. The company's product revenue saw a decline of 9.3% to $52.1 million, impacted by decreased sales of in-licensed products like ABRAXANE and REVLIMID, as well as the suspension of ABRAXANE sales in China due to regulatory issues. However, the initial sales of its internally developed drugs, tislelizumab and BRUKINSA, provided some offset. Investors should note the significant increase in R&D spending, reflecting continued investment in pipeline development, and the ongoing impact of COVID-19 on commercial operations.

Financial Statements
Beta

Key Highlights

  • 1Total cash, cash equivalents, and short-term investments increased significantly to $3.4 billion as of March 31, 2020, primarily due to $2.78 billion in proceeds from the Amgen collaboration.
  • 2Net loss widened to $364.9 million for Q1 2020, from $168.1 million in Q1 2019.
  • 3Research and development (R&D) expenses increased by 70.6% to $304.3 million, driven by advancements in clinical drug candidates and collaboration expenses.
  • 4Selling, general, and administrative (SG&A) expenses increased by 85.8% to $107.1 million, primarily due to increased headcount to support growing operations.
  • 5Total revenues decreased by 33.1% to $52.1 million, mainly due to the absence of collaboration revenue from the terminated BMS agreement and a 9.3% decrease in product revenue.
  • 6Product revenue declined 9.3% to $52.1 million, impacted by lower sales of in-licensed products and the suspension of ABRAXANE sales in China, partially offset by initial sales of tislelizumab and BRUKINSA.
  • 7The company's net loss per ADS was $(4.70) for Q1 2020, compared to $(2.81) for Q1 2019.

Frequently Asked Questions

The primary driver for the substantial increase in cash and cash equivalents was the financing activity, specifically the proceeds received from the strategic collaboration with Amgen, which amounted to $2.78 billion. This significantly boosted the company's liquidity.

The net loss increased significantly due to a substantial rise in operating expenses. Research and development (R&D) expenses grew by 70.6% to $304.3 million, and selling, general, and administrative (SG&A) expenses increased by 85.8% to $107.1 million. These higher expenses, coupled with a decrease in total revenue, led to a wider net loss.

Product revenue decreased by 9.3% to $52.1 million. This decline was primarily due to lower sales volumes for in-licensed products like ABRAXANE® and REVLIMID®, a suspension of ABRAXANE® sales in China due to regulatory inspection findings, and the impact of COVID-19. These factors were partially offset by the initial sales of the company's internally-developed products, tislelizumab and BRUKINSA™.

The collaboration with Amgen, effective January 2, 2020, provided $2.78 billion in cash proceeds, recorded as $2.16 billion to equity and $0.62 billion as a research and development cost share liability. This significantly strengthened the company's balance sheet and liquidity. The company also incurs co-development costs under this agreement, with $28.4 million recorded as R&D expense in Q1 2020.