01—Abstract
Summary
Summary of the 8-K filed April 30, 2026. Cited figures are marked; the original filing is the authoritative source.
Illumina, Inc. (Nasdaq: ILMN) reported first-quarter 2026 results for the quarter ended March 29, 2026, per an 8-K filed April 30, 2026 that furnishes a press release as Exhibit 99.1.
Revenue was $1.09 billiona, up 4.8% from $1.04 billion in Q1 2025, with ROW organic revenue growth of 3.5%. GAAP operating margin was 19.2% and non-GAAP operating margin was 21.9%. GAAP diluted EPS was $0.87 and non-GAAP diluted EPS was $1.15, compared with $0.82 and $0.97 a year earlier.
Net income was $134 millionb, and free cash flow was $251 million, up from $208 million. Management raised fiscal 2026 guidance. Total revenue is now expected at $4.52-$4.62 billion, a $20 million increase at the midpoint, while reported revenue growth of 4%-6% and ROW organic growth of 2%-4% are unchanged.
Non-GAAP operating margin guidance moved to 23.4%-23.6% from 23.3%-23.5%, and non-GAAP diluted EPS guidance moved to $5.15c-$5.30 from $5.05-$5.20. The CEO attributed demand to NovaSeq X adoption by clinical customers expanding into new application areas.
Separately, the Board authorized on April 28, 2026 a new share repurchase program of up to $1.5 billiond, in addition to the August 2024 program under which approximately $314 million of capacity remained as of April 29, 2026. Cash, cash equivalents and short-term investments totaled $1.16 billion at quarter end, and total term debt was $1.99 billion ($499 million current plus $1.49 billion long-term).
02—Key points
Key Highlights
- Q1 2026 revenue of $1.09 billion, up 4.8% from $1.04 billion in Q1 2025; ROW organic revenue growth was 3.5%
- GAAP diluted EPS of $0.87 versus $0.82 a year earlier; non-GAAP diluted EPS of $1.15 versus $0.97
- Non-GAAP operating margin of 21.9% versus 20.4% in Q1 2025; GAAP operating margin of 19.2% versus 15.8%
- Fiscal 2026 total revenue guidance raised to $4.52-$4.62 billion, a $20 million increase at the midpoint
- Non-GAAP diluted EPS guidance raised to $5.15-$5.30 from $5.05-$5.20; non-GAAP operating margin guidance raised to 23.4%-23.6%
- Free cash flow of $251 million for Q1 2026, compared with $208 million in Q1 2025
- New share repurchase authorization of up to $1.5 billion approved April 28, 2026, on top of about $314 million remaining under the August 2024 program
03—Questions
Frequently Asked Questions
How did Illumina perform in the first quarter of 2026?
Revenue was $1.09 billion, up 4.8% from $1.04 billion a year earlier. GAAP net income was $134 million, or $0.87 per diluted share, compared with $131 million, or $0.82 per diluted share, in Q1 2025. Non-GAAP diluted EPS was $1.15 versus $0.97.
Did Illumina change its full-year 2026 guidance?
Yes, it raised guidance. Total revenue is now $4.52-$4.62 billion, a $20 million increase at the midpoint. Reported revenue growth of 4%-6% and ROW organic revenue growth of 2%-4% were unchanged. Non-GAAP operating margin is now 23.4%-23.6% (previously 23.3%-23.5%), and non-GAAP diluted EPS is $5.15-$5.30 (previously $5.05-$5.20).
What share repurchase activity did the company announce?
On April 28, 2026, the Board authorized a new program for up to $1.5 billion of common stock. This is in addition to the $1.5 billion program authorized in August 2024, under which approximately $314 million of capacity remained as of April 29, 2026.
What was Illumina's cash and debt position at quarter end?
At March 29, 2026, cash and cash equivalents were $1.09 billion and short-term investments were $66 million, totaling $1.16 billion. Term debt was $1.99 billion, including $499 million classified as current and $1.49 billion long-term. Stockholders' equity was $2.68 billion.
What drove the difference between GAAP and non-GAAP results?
Non-GAAP results exclude items such as acquisition-related costs, which were $0.15 per diluted share in Q1 2026, and a $0.24 per share net strategic investment loss. Acquisition-related costs were primarily related to the SomaLogic acquisition, including amortization of intangible assets, legal and other expenses, and an inventory step-up, partly offset by a $16 million fair value gain on contingent consideration. Transformational initiatives, primarily ERP implementation costs, added $0.04 per share.
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