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United Therapeutics Quarterly Report for Q2 Ended Jun 30, 2025

Filing Date
Filed July 30, 2025
Period End
June 30, 2025
Security
UTHR
One revenue dollarkept$0.39
In the record · 2016–202610-K1110-Q338-K152

UTHR filed 11 annual reports (10-K), 33 quarterly reports (10-Q) and 152 current reports (8-K) between 2016 and 2026.

  1. Leadership change8-K · Jun ’18Jun ’18
  2. Change in control8-K · Jun ’20Jun ’20
  3. Leadership change8-K · Jun ’22Jun ’22
  4. Material agreement8-K · Sep ’26Sep ’26

Summary

Summary of the 10-Q filed July 30, 2025. Cited figures are marked; the original filing is the authoritative source.

United Therapeutics Corporation's Form 10-Q for the quarter ended June 30, 2025 reports total revenues of $798.6 milliona for the three months ended June 30, 2025, up from $714.9 million a year earlier, and $1,593.0 million for the six months, versus $1,392.6 million.

Net income was $309.5 millionb for the quarter (diluted EPS $6.41) and $631.7 million for the six months (diluted EPS $13.02). Growth was driven mainly by Tyvaso DPI, whose net product sales rose 22% in the quarter to $315.2 million, and by Orenitram and Unituxin. Remodulin sales declined 9% in the quarter, and the filing notes Liquidia's Yutrepia received FDA approval in May 2025 and launched in June 2025, competing directly with Tyvaso products.

The company reported $1,593.1 millionc in cash and cash equivalents and total cash and marketable investments of $4,966.4 million. Its outstanding balance under the 2025 Credit Agreement, a $2.5 billion unsecured revolver, was zero as of June 30, 2025, after the company repaid the $200.0 million drawn in April. The filing describes significant pending litigation, including a Sandoz judgment with an accrued liability of $71.1 million recorded in 2024 plus $1.5 million accrued through the second quarter of 2025, and an ongoing patent case against Liquidia where trial took place in June 2025.

The company also disclosed $21.7 milliond in impairment of property, plant, and equipment and budgeted approximately $710 million in capital expenditures from the third quarter of 2025 through the end of 2027. On July 25, 2025, the board authorized a $1.0 billion share repurchase program expiring March 31, 2026.

Key Highlights

  1. Total revenues rose to $798.6 million in Q2 2025 from $714.9 million in Q2 2024; six-month revenues were $1,593.0 million versus $1,392.6 million.
  2. Tyvaso DPI net product sales were $315.2 million in the quarter, up 22% year over year, and Total Tyvaso net product sales grew 18% to $469.6 million.
  3. Net income was $309.5 million for the quarter (diluted EPS $6.41) versus $278.1 million (diluted EPS $5.85) a year earlier; six-month net income was $631.7 million.
  4. Cash and cash equivalents plus marketable investments totaled $4,966.4 million at June 30, 2025, and the $2.5 billion revolving credit facility had no outstanding balance.
  5. Liquidia's Yutrepia received FDA approval in May 2025 and launched in June 2025; the company stated it has not yet seen a material impact on Tyvaso DPI revenues.
  6. Litigation remains significant: a Sandoz judgment accrual of $71.1 million (2024) plus $1.5 million through Q2 2025, and the Liquidia '327 patent case went to trial in June 2025.
  7. The board authorized a $1.0 billion share repurchase on July 25, 2025, and the company budgeted about $710 million in capital expenditures for Q3 2025 through 2027.

Follow one dollar

Of each $1.00 of revenue in Q2 FY2025, United Therapeutics kept $0.39.

  1. Revenue$798.6M100.0%
  2. Cost of revenue−$87.6M11.0%
  3. Gross profit$711.0M89.0%
  4. Operating costs−$346.5M43.4%
  5. Operating income$364.5M45.6%
  6. Interest, other & tax−$55.0M6.9%
  7. Net income$309.5M38.8%
Computed from 10-QQ2 FY2025filed July 30, 2025Computed from this filing’s revenue, gross profit, operating income and net income · right columngrey figure: share of revenue

Financial Statements

Q2 FY2025 against Q2 FY2024

Line itemQ2 FY2025Q2 FY2024Change
Revenue$798.60M$714.90M+11.7%
Cost of Revenue$87.60M$77.80M+12.6%
Gross Profit$711.00M$637.10M+11.6%
R&D Expenses$134.00M$139.60M−4.0%
SG&A Expenses$212.50M$177.60M+19.7%
Operating Expenses$434.10M$395.00M+9.9%
Operating Income$364.50M$319.90M+13.9%
Net Income$309.50M$278.10M+11.3%
EPS (Basic)$6.86$6.26+9.6%
EPS (Diluted)$6.41$5.85+9.6%
Shares Outstanding (Basic)45.10M44.40M+1.6%
Shares Outstanding (Diluted)48.30M47.50M+1.7%

Frequently Asked Questions

  1. How did revenue and profitability trend in the second quarter of 2025?

    Total revenues increased to $798.6 million from $714.9 million, and net income rose to $309.5 million from $278.1 million. Diluted EPS was $6.41 versus $5.85. Operating income was $364.5 million versus $319.9 million, with SG&A and R&D expenses rising in the period.

  2. What is driving growth in the product portfolio?

    Tyvaso DPI net product sales increased 22% in the quarter to $315.2 million, driven by higher quantities sold and a price increase, partly offset by higher gross-to-net deductions. Orenitram rose 16% to $123.9 million, while Remodulin declined 9% to $134.7 million, reflecting generic competition.

  3. What is the company's liquidity position?

    Cash and cash equivalents were $1,593.1 million and marketable investments totaled $3,373.3 million, for a combined $4,966.4 million at June 30, 2025. The company repaid its $200.0 million drawn under the 2025 Credit Agreement, leaving no outstanding balance on the $2.5 billion facility.

  4. What are the main risks highlighted in the filing?

    Key risks include generic and new competition, most notably Liquidia's Yutrepia; ongoing litigation including the Sandoz judgment appeal, the Liquidia patent case, and charity-related RICO suits from Humana, United, and MSP Recovery; pricing pressure from the IRA and most favored nation proposals; and reliance on third-party manufacturers and distributors.

  5. What capital allocation actions and commitments were disclosed?

    The company budgeted approximately $710 million for capital expenditures from the third quarter of 2025 through the end of 2027, primarily for a Tyvaso DPI facility in RTP and designated pathogen-free facilities. On July 25, 2025, the board authorized a $1.0 billion share repurchase expiring March 31, 2026, and it acquired property in Research Triangle Park for $107.0 million in July 2025.